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Manufacturing facilities sometimes process multiple products, which could be a concern for those with severe allergies

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MAJOR FEATURES OF THE LESION (2 points each): Change in size Irregular shape Irregular colour MINOR FEATURES OF THE LESION (1 point each): Largest diameter 7mm or more Inflammation Oozing Change in sensation Patients should also be referred urgently (within 2 weeks) if dermoscopy suggests melanoma skin cancer and if a pigmented or non-pigmented skin lesion is suggestive of nodular melanoma or other forms of rarer skin cancers

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Drug safety 22 , 123148 (2000)

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However, excessive use or improper formulation can increase the risk of copper toxicity and adverse reactions

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